Loureirin A

CAS No. 119425-89-7

Loureirin A ( —— )

Catalog No. M19777 CAS No. 119425-89-7

Loureirin A has an inhibitory effect on platelet activation perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen collagen-related peptide (CRP) ADP and thrombin.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 132 In Stock
10MG 196 In Stock
25MG 332 In Stock
50MG 489 In Stock
100MG 698 In Stock
500MG 1413 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Loureirin A
  • Note
    Research use only not for human use.
  • Brief Description
    Loureirin A has an inhibitory effect on platelet activation perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen collagen-related peptide (CRP) ADP and thrombin.
  • Description
    Loureirin A has an inhibitory effect on platelet activation perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen collagen-related peptide (CRP) ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4inhibiting the synthesis and secretion of α- SMATGF- β1and the proliferation of HSCs.
  • Synonyms
    ——
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PI3K
  • Recptor
    PI3K
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    119425-89-7
  • Formula Weight
    286.32
  • Molecular Formula
    C17H18O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 86.6 mg/mL (302.46 mM)
  • SMILES
    COc1ccc(CCC(=O)c2ccc(O)cc2)c(OC)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hao H Z He A D Wang D C et al. Antiplatelet activity of loureirin A by attenuating Akt phosphorylation: In vitro studies[J]. European Journal of Pharmacology 2015 746:63-69.
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