Loureirin A
CAS No. 119425-89-7
Loureirin A ( —— )
Catalog No. M19777 CAS No. 119425-89-7
Loureirin A has an inhibitory effect on platelet activation perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen collagen-related peptide (CRP) ADP and thrombin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 132 | In Stock |
|
10MG | 196 | In Stock |
|
25MG | 332 | In Stock |
|
50MG | 489 | In Stock |
|
100MG | 698 | In Stock |
|
500MG | 1413 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NameLoureirin A
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NoteResearch use only not for human use.
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Brief DescriptionLoureirin A has an inhibitory effect on platelet activation perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen collagen-related peptide (CRP) ADP and thrombin.
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DescriptionLoureirin A has an inhibitory effect on platelet activation perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen collagen-related peptide (CRP) ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4inhibiting the synthesis and secretion of α- SMATGF- β1and the proliferation of HSCs.
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorPI3K
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Research Area——
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Indication——
Chemical Information
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CAS Number119425-89-7
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Formula Weight286.32
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Molecular FormulaC17H18O4
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 86.6 mg/mL (302.46 mM)
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SMILESCOc1ccc(CCC(=O)c2ccc(O)cc2)c(OC)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hao H Z He A D Wang D C et al. Antiplatelet activity of loureirin A by attenuating Akt phosphorylation: In vitro studies[J]. European Journal of Pharmacology 2015 746:63-69.
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